Under each slot, I have listed the item enhancements generally in order from the best enhancement to least best. For most slots, I have a couple of options and ranked them this way, so that if you do not want to spend all the mats on the best enchantment (i.e. on a non-epic item that you will hopefully replace soon, etc), you can find a cheaper alternative that is still good. If you're still in greens and don't want to spend money on expensive enchants, at least pick up some Heavy Borean Armor Kits for the applicable unenchanted slots.

Some points to consider about my rankings:

• In general, these suggestions apply for both Holy AND Discipline specced PvE healers. The only caveat to that is that Discipline priests are more likely to choose Spellpower enchantments over mana regen enchantments, particularly if the mana regen is Spirit (i.e. Chest, Feet, and Wrists)
• If you are not having any mana troubles, you may choose enchancements that give a bonus to crit or haste over mana regen (For instance, I use Arcanum of Burning Mysteries instead of Arcanum of Blissful Mending). This is perfectly fine.
  
• If you primarily heal in 5 mans or (to a lesser degree) 10 mans, you are more likely to encounter mana problems, and I highly recommend you opt for mana regen enchantments.
• You can also refer to Elitistjerks for their BiS enchants, as there are a few variations from my choices.
  

Standard Enchantments (Done by an Enchanter)

Chest:

• Greater Mana Restoration (420) (This is best for Holy Priests - if you are Holy, ignore the "Stats" to chest enchants. If you are Disc, do NOT get this enchant - you don't need it)
  
• Powerful Stats (440) (Best for Disc)
  
• Super Stats (370)
  

Feet:

• Greater Spirit (410) (Disc Priests everywhere weep)
  
• Greater Vitality (405)
  

Wrists:

• Superior Spellpower (440)
  
• Major Spirit (420)
  
• Greater Spellpower (395)
  

Hands:

• Exceptional Spellpower (360)
  

Cloak (Engineers and Tailors have other options, see below):

• Greater Speed (430)
  
• Speed (350)
  
• Wisdom (440)
  

2 Hand Weapon (Staff):

• Greater Spellpower (450)
  
• Spellpower (385)
  

1 Hand Weapon (Dagger or Mace):

• Mighty Spellpower (435)
  
• Exceptional Spellpower (395)
  
• Exceptional Spirit (410) (Disc priests stay awaaaay)
  

In addition, Enchanters may enchant their own rings with Greater Spellpower (you cannot have an enchanter do this for you, as it makes the item permanently soulbound).

Arcanums (Headpiece Enhancements)

• Arcanum of Blissful Mending (Holy until you have no mana problems) or Arcanum of Burning Mysteries (Disc and advanced Holy)
• Arcanum of Renewal (requires Revered reputation with Thrallmar / Honor Hold from the Outlands)
  

Inscriptions (Shoulder Enhancements)

• Greater Inscription of the Crag (Holy until you have no mana problems)or Greater Inscription of the Storm (Disc and advanced Holy)
  
• Lesser Inscription of the Crag or Lesser Inscription of the Storm
• Inscription of Dominance - pick this up until you grind enough Sons of Hodir rep. Only costs 30 Stonekeepers Shards in WG.
  

Scribes do not need to grind reputation - they have the ability to Inscribe their own shoulders at level 400 with much better inscriptions: Master's Inscription of the Storm or Master's Inscription of the Crag.

Spellthreads (Leg Enhancements)

• Brilliant Spellthread
  
• Shining Spellthread
• Mystic Spellthread or Silver Spellthread

There is no enhancement for Neck, Trinkets, Off-Hand Items, or Wands, although Alchemists, Jewelcrafters, and Engineers can make their own trinkets, and obviously various professions can make different other items. Although this post is not intended to be a guide to which professions are best for the healing priest at end game, I would be remiss if I did not list some of the other item enhancements that different professions offer only for themselves. These profession specific item enhancements CANNOT be stacked with standard enchants, but are usually superior anyway.

Tailors have two Cloak embroidery options that are better than the Cloak Enchants:

• Lightweave Embroidery - This is a pretty substantial increase to healing throughput, but I do not use it because you cannot rely on the increase when you need it. I won't notice that it procs, and just continue my job as usual (/shrug).
  
• Darkglow Embroidery - I prefer this embroidery, as over the duration of a fight, it procs often enough (~35% proc, ~60s ICD) to give me a reliable "mana regen" boost. Good choice for priests, who use a lot of instant or short casts.
  

Engineers:

• Springy Arachnoweave - The basic stats on this enchantment alone are much better than the haste enchants offered by Enchanters, even if you never use the parachute because you have Levitate.
  
• Hyperspeed Accelerators - This is a fantastic haste increase, and really more like an extra trinket with a short cooldown. You can tie this to a macro and use it every ten seconds, or use it fairly regularly, and save the burst haste for when you are in a healing crisis and need to get a heal on someone ASAP. Does not activate GCD and stacks with other group/raid haste buffs (i.e. Heroism).
  
• Nitro Boosts - Unless you are really desperate for mana regen, this is far superior to the crappy boot enchants. Also, the run speed increase can get you out of bad spots in a jiffy (zomg eyebeam), or if someone is stupidly out of your healing range and dying, get you closer to them to save their butts (I'm looking at you, mages!)

Leatherworkers:

• Fur Lining - Spellpower - Vastly superior to the so-called Superior Spellpower.
  

Don't forget to pick up an Eternal Belt Buckle for your waist (made by blacksmiths) to add another gem socket. In addition, Blacksmiths can add a socket to their own bracers and their own gloves.



Edited October 6th: Clarified more between Disc and Holy differences.
Edited October 9th: Added super pro tip from Fido about inscription of Dominance!

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There's a really awesome website that I use whenever I'm deciding on gems called WoW Gem Finder. I was looking back through my Holy Priest Healing Guide, and realized that I never mentioned enchants or gems.  Enchants for another day, but I'll hit up gems now. I highly recommend checking out elitistjerks for gem suggestions if you are interested in the theorycrafting behind choices, though they have not updated with the new epic gems on the linked post - it's likely you will need to read through the thread.

However, I'm anal retentive, and cannot bear to lose a socket bonus, which EJ often ignores. Therefore, I always use a matching color for the socket. I find it handy to know what stats are related to which colors, so here you go.

Yellow Sockets: Intellect, Critical Strike Rating, Hit Rating, Resilience, Haste, Defense Rating
Red Sockets: Strength, Attack Power, Agility, Parry, Armor Penetration, Expertise, Spell Power, Dodge Rating
Blue Sockets: Stamina, Mp5, Spirit, Spell Penetration

You can see, just by looking at the color -> stat conversions that Red Sockets are for spellpower, Blue Sockets are for regen via spirit/mp5, and Yellow is for all the fun stuff. I've italicized the stats that are generally useless for priest gemming in PvE raid healing. You could argue that stamina is a good choice, but unlike the days of Primal Mooncloth sets, we don't really need to gem for stamina anymore, as we get plenty naturally from our gear.

For blue sockets, I always choose Spirit over Mp5 due to Spiritual Guidance. Maybe mp5 is actually better, and if I wanted to, I could do some maths, but like, math is hard, so... no. Spirit it is (see, this is why I recommended elitistjerks!). I never use a solid blue gem for my blue sockets - if I need more mana, it's better to use Intellect, at least for raiders. For mages and warlocks who are determined to take advantage of socket bonuses as well, spirit may be a better choice for you too, due to talents boosting spellpower through spirit.

For Red, of course I always choose spell power, since there aren't any other good choices.

Where you really start to see differences among priest choices and gear levels comes in the yellow socket. When you are first starting out, always pick Intellect for more mana and mana regen. Once you have a solid mana pool and no longer need to panic about your mana sustainability (which, for the record, is a lot easier in 25 man raids due to more buffs), you can start picking up crit and/or haste. I try to balance between the two stats, but plenty of people have a preference for one over the other.

Now that I have so much intellect, mana is rarely an issue for me, nor is crit. I prefer to gem for Intellect over crit, since you do get some crit boost from intellect. However, I do not necessarily recommend this if you really do need a lot more crit.

I've listed my top choices for each color socket. The first gem is the epic, the second is the rare gem equivalent. If you are not yet ready to blow large amounts of gold on the epic gems (new to raiding, doing heroics, 5 mans, etc), pick up the lesser gem with similar stats.

Yellow:

• Haste: Quick King's Amber / Quick Autumn's Glow
  
• Intellect: Brilliant King's Amber / Brilliant Autumn's Glow
  
• Crit: Smooth King's Amber / Smooth Autumn's Glow
  

Red:

• Spellpower: Runed Cardinal Ruby / Runed Scarlet Ruby
  
• Spellpower + Intellect: Luminous Ametrine / Luminous Monarch Topaz
  
• Spellpower + Haste: Reckless Ametrine / Reckless Monarch Topaz
  
• Spellpower + Crit: Potent Ametrine / Potent Monarch Topaz
  

Blue:

• Spirit + Spellpower: Purified Dreadstone / Purified Twilight Opal
  
• Spirit + Intellect: Seer's Eye of Zul / Seer's Forest Emerald
  
• Spirit + Crit: Misty Eye of Zul / Misty Forest Emerald
  
• Spirit + Haste: Intricate Eye of Zul / Intricate Forest Emerald
  

I usually pick my gems based around current prices as well. Runed Cardinal Ruby is always ridiculously expensive, so I look for different combinations that will add up to the same amount.

For example: Let us suppose that I have Savior's Slippers, with one red socket and one blue socket. Instead of choosing Runed Cardinal Ruby + Sparkling Majestic Zircon, I may find that it is cheaper to socket 2x Purified Dreadstone, which would actually give me +1 spellpower over a Runed Cardinal Ruby which is usually very expensive.

In reality, it is unlikely I would use any gem that has spirit on it in anything other than a blue socket, but you get the point. Creative combinations and careful shopping can save you lots of gold on gems, and potentially net you better rewards. For Blue Sockets, I always use a combination gem. For Yellow sockets, I always use a solid yellow gem. For red sockets, it depends on the current price of Runed Cardinal Rubies.

In short? Don't gem for spirit or mp5. If you need to use a blue gem (socket bonus, meta bonus, etc), use a purple or green gem that includes spirit. If you need mana regen as a raider, gem for Intellect (this is slightly less true for those who focus on 5 mans - the more people in your group, the higher the chance you will receive more benefits from intellect regen opportunities). Once you have enough mana, pick up crit or haste. Always gem for spellpower. Combine multi-colored gems to save some gold.

Meta Gems

For your Meta Socket, the following are the only real options for a Holy PvE Priest:

• Beaming Earthsiege Diamond - Easy socket requirement to achieve. If you are in need of a lot of extra crit, this is a pretty good choice.
  
• Bracing Earthsiege Diamond - Threat should NOT be an issue for you. If it is, there are more important problems to address. The only time that threat may potentially be a significant problem is in 5 mans with a fresh tank who is learning the ropes. Therefore, this is ONLY a decent choice if you are with a group just starting 5 man heroics, etc.
  
• Insightful Earthsiege Diamond - My favorite meta. The mana restoration proc happens quite a bit for Holy Priests, as we are often using lots of instant heals mixed in with quickie flash heals.
  
• Ember Skyflare Diamond - Always a solid choice. Insightful meta is better until you build up solid mana reserves, at which point this becomes a great meta, particularly since it scales so well with gear.
  
• Revitalizing Skyflare Diamond - Don't be bad. Blizzard put this here just to trick you. Just say no to "increased crit heal effect" which half of the time translates into "increased overheal amount and therefore a complete waste NYAH NYAH". You canNOT rely on crits when a heal is needed, and "increased critical healing effect" is very different than increased spellpower, which is RELIABLE. Also, I recommend Spirit or Intellect over mp5.
  

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